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https://ir.iimcal.ac.in:8443/jspui/handle/123456789/1707| Title: | Decision-based Biochips: A novel design for concurrent execution of networked bioassays integrated in scalable DMFBs |
| Authors: | Roy, Pranab Chakraborty, Mriganka Bal, Aatreyi Rahaman, Hafizur Dasgupta, Partha Sarathi |
| Keywords: | Bioassay Protocols Decision-based execution Detection and analysis Digital Microfluidics Droplet detection analyzer Integration Photodiode |
| Issue Date: | 2015 |
| Publisher: | SCOPUS Proceedings of the 6th Asia Symposium on Quality Electronic Design, ASQED 2015 Institute of Electrical and Electronics Engineers Inc. |
| Abstract: | Digital Microfluidic Biochips, a promising platform for Lab-on-chip systems are capable of automated biochemical analysis targeted for medical diagnostics and other biochemical applications. Due to its reconfigurability and scalability, a DMFB device is capable of integrating multiple bioassay protocols within the same array for simultaneous execution. We propose a DMFB design capable of executing multiple Bioassays selectively based on prior detection of results of already executed protocols at previous timestamps. We propose specified detection analyzers to be integrated with photodiodes preplaced at dedicated detection sites and a centralized memory to decide on the predefined signal set for a given execution sequence. The simulation is carried out using FPGA prototypes integrated with a DMFB with a prespecified layout for multilevel execution and the results are found to be in conformance with conventional benchtop procedures. © 2015 IEEE |
| Description: | Roy, Pranab, School of VLSI Technology, Indian Institute of Engineering Science and Technology, Shibpur, India; Chakraborty, Mriganka, School of VLSI Technology, Indian Institute of Engineering Science and Technology, Shibpur, India; Bal, Aatreyi, School of VLSI Technology, Indian Institute of Engineering Science and Technology, Shibpur, India; Rahaman, Hafizur, School of VLSI Technology, Indian Institute of Engineering Science and Technology, Shibpur, India; Dasgupta, Partha Sarathi, Indian Institute of Management, Calcutta, India ISSN/ISBN - 978-146737495-8 pp.138-143 DOI - 10.1109/ACQED.2015.7274023 |
| URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84962085880&doi=10.1109%2fACQED.2015.7274023&partnerID=40&md5=7f9231e092ef07d81569f5244dfcd20b https://ir.iimcal.ac.in:8443/jspui/handle/123456789/1707 |
| Appears in Collections: | Management Information Systems |
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